⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762009 | 0.78 | — | — | |
| SCHEMBL1605178 | 0.74 | — | — | |
| SCHEMBL10658864 | 0.74 | — | — | |
| SCHEMBL9183607 | 0.72 | — | — | |
| SCHEMBL1078119 | 0.72 | — | — | |
| SCHEMBL10533446 | 0.71 | — | — | |
| SCHEMBL11291723 | 0.71 | — | — | |
| SCHEMBL9186887 | 0.69 | — | — | |
| SCHEMBL10698875 | 0.69 | — | — | |
| SCHEMBL11167329 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928787-B1 | Process for the preparation of 3-amino-pyrrolidine derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1138672-A1 | Process for the preparation of 3-amino-pyrrolidine derivatives | Basilea Pharmaceutica AG (CH) | 2001-10-04 | — | — | EP | disclosed |
| US-5977381-A | Process for making 3-amino-pyrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0928787-A1 | Process for the preparation of 3-amino-pyrrolidine derivatives | F. Hoffmann-La Roche AG (CH) | 1999-07-14 | — | — | EP | disclosed |