Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541602 | 1.00 | GRN (0.41) | GRNSORT1ALDH1A1LMNAITGB1 | |
| SCHEMBL7545718 | 0.93 | ITGB1 (0.45) | ITGB1ITGA4MAPT | |
| SCHEMBL7541296 | 0.93 | ITGB1 (0.45) | ITGB1ITGA4MAPT | |
| SCHEMBL7544936 | 0.93 | ITGB1 (0.41) | ITGB1ITGA4MAPTANPEPFPR2 | |
| SCHEMBL7541044 | 0.93 | ITGB1 (0.42) | ITGB1ITGA4MAPK1MAPTANPEP | |
| SCHEMBL7547298 | 0.93 | ITGB1 (0.42) | ITGB1ITGA4MAPK1MAPTANPEP | |
| SCHEMBL7544863 | 0.93 | ITGB1 (0.41) | ITGB1ITGA4MAPTANPEPFPR2 | |
| SCHEMBL7565957 | 0.91 | ANPEP (0.50) | ALDH1A1ITGB1ITGA4MAPTANPEP | |
| SCHEMBL7539262 | 0.91 | ANPEP (0.50) | ALDH1A1ITGB1ITGA4MAPTANPEP | |
| SCHEMBL7538590 | 0.91 | GRN (0.45) | GRNSORT1ALDH1A1LMNAITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |