SCHEMBL754103

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754104	1.00	PDE3B (0.37)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL27588457	0.77	CNR2 (0.37)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL755018	0.77	PDE3B (0.37)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL753145	0.77	CNR2 (0.37)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL753146	0.77	CNR2 (0.37)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL753269	0.77	CNR2 (0.38)	KMT2ANPSR1PTGS2PTGS1PTGDR2
	SCHEMBL751978	0.73	MAPT (0.41)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL751977	0.73	MAPT (0.41)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL16921581	0.72	PDE3B (0.42)	PDE3BPDE3AMAPTMEN1KMT2A
	SCHEMBL2485045	0.72	MAPK14 (0.42)	MEN1KMT2ANPSR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.