Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541809 | 1.00 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27889350 | 0.91 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6832939 | 0.87 | — | — | |
| SCHEMBL6832938 | 0.87 | — | — | |
| SCHEMBL15477716 | 0.85 | — | — | |
| SCHEMBL12723966 | 0.85 | — | — | |
| SCHEMBL29058053 | 0.84 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL34966 | 0.83 | — | — | |
| SCHEMBL19134443 | 0.83 | — | — | |
| SCHEMBL28763154 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732098-B1 | Polymerizable composition | DENTSPLY DETREY GMBH (DE) | 2002-06-05 | — | — | EP | claimed |
| US-5688883-A | CATALYTIC POLYMERIZATION OF ACRYLATES FOR DENTAL SEALS OR ADHESIVES | DENTSPLY GMBH (DE) | 1997-11-18 | — | — | US | claimed |
| EP-0732098-A2 | Polymerizable composition | DENTSPLY DETREY GmbH (DE) | 1996-09-18 | — | — | EP | claimed |