Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881032 | 0.82 | KDM4E (0.54) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL73570 | 0.81 | KDM4E (0.54) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL73113 | 0.81 | HPGD (0.59) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL75565 | 0.79 | KDM4E (0.51) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL10929709 | 0.78 | HPGD (0.56) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL6244428 | 0.77 | KDM4E (0.49) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL20718077 | 0.77 | KDM4E (0.60) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL4882291 | 0.76 | KDM4E (0.48) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL15143918 | 0.75 | SMN1; SMN2 (0.79) | KDM4EHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL17904708 | 0.75 | NPC1 (0.67) | KDM4EHPGDNPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |