Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.48 |
| ▸ | PPARA | Q07869 | 17/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380851 | 0.88 | KDR (0.50) | PPARGPPARAKDRFFAR1 | |
| SCHEMBL5371963 | 0.87 | PPARG (0.48) | PPARGPPARAKDRFFAR1 | |
| SCHEMBL5383028 | 0.86 | PPARG (0.50) | PPARGPPARAFFAR1 | |
| SCHEMBL6593852 | 0.84 | PPARG (0.49) | PPARGPPARAKDRFFAR1 | |
| SCHEMBL6593860 | 0.84 | PPARG (0.49) | PPARGPPARAKDRFFAR1 | |
| SCHEMBL5392056 | 0.83 | FFAR1 (0.58) | PPARGPPARAFFAR1 | |
| SCHEMBL5372026 | 0.81 | PPARG (0.47) | PPARGPPARAKDRFFAR1 | |
| SCHEMBL5372022 | 0.81 | PPARG (0.48) | PPARGPPARAFFAR1 | |
| SCHEMBL5385634 | 0.81 | PPARG (0.49) | PPARGPPARAFFAR1 | |
| SCHEMBL4034034 | 0.81 | KDR (0.65) | PPARGPPARAKDRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |