Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371972 | 0.92 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL5376708 | 0.87 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5373778 | 0.85 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5385527 | 0.84 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL7540297 | 0.84 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL5382403 | 0.82 | FFAR1 (0.57) | PPARGPPARA | |
| SCHEMBL5371969 | 0.80 | KDR (0.48) | PPARGPPARA | |
| SCHEMBL5381008 | 0.80 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5372574 | 0.80 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL5382079 | 0.79 | PPARG (0.62) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |