Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540772 | 1.00 | ACE (0.42) | ACEITGB1ITGA4MMP2FPR2 | |
| SCHEMBL7541939 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4MMP2FPR2MAPT | |
| SCHEMBL7546281 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4MMP2FPR2MAPT | |
| SCHEMBL7538982 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4MMP2FPR2MAPT | |
| SCHEMBL7541947 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4MMP2FPR2MAPT | |
| SCHEMBL7540012 | 0.93 | ITGB1 (0.40) | ITGB1ITGA4MMP2FPR2MAPT | |
| SCHEMBL7545785 | 0.92 | ITGB1 (0.46) | ACEITGB1ITGA4MMP2FPR2 | |
| SCHEMBL7538562 | 0.92 | ANPEP (0.49) | ACEITGB1ITGA4FPR2MAPT | |
| SCHEMBL7545838 | 0.92 | ANPEP (0.49) | ACEITGB1ITGA4FPR2MAPT | |
| SCHEMBL7547950 | 0.90 | ACE (0.46) | ACEITGB1ITGA4FPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |