Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25297773 | 1.00 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL1864772 | 1.00 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL18230615 | 0.98 | EP300 (0.59) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL10805025 | 0.98 | EP300 (0.59) | EP300PPARGPPARATERTPTPN1 | |
| Ethylene SCHEMBL17728021 | 0.96 | EP300 (0.58) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3421630 | 0.92 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL11027652 | 0.92 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL20954084 | 0.92 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL20954083 | 0.92 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3711652 | 0.92 | EP300 (0.62) | EP300PPARGPPARATERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020197732-A1 | Method and apparatus for combinatorial screening of polymer compositions | GENERAL ELECTRIC COMPANY | 2002-12-26 | — | — | US | disclosed |
| US-4444935-A | Compositions comprising a thermoplastic resin and an acrylate mold release agent | GENERAL ELECTRIC COMPANY (US) | 1984-04-24 | — | — | US | disclosed |