Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814288 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL8811143 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL8811977 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL8810628 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL8813527 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL8813126 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL8812361 | 1.00 | TSHR (0.44) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL13609143 | 0.98 | TSHR (0.41) | TSHRFAAHTRPV1HIF1APRKCA | |
| SCHEMBL9844952 | 0.91 | — | — | |
| SCHEMBL8810617 | 0.88 | TSHR (0.41) | TSHRFAAHTRPV1HIF1APRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885886-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN SEIFUN GROUP INC (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5972943-A | N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885886-A1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| CN-1033227-C | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and their use. | SANKYO CO (JP) | 1996-11-06 | — | — | CN | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| CN-1072686-A | Has Pyrmidine nucleoside derivatives of anti-tumor activity and its production and use | SANKYO CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |