Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 19/20 | 0.73 |
| ▸ | RARB | P10826 | 17/20 | 0.73 |
| ▸ | RARA | P10276 | 16/20 | 0.73 |
| ▸ | RXRA | P19793 | 13/20 | 0.73 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544450 | 1.00 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7544453 | 0.91 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7544446 | 0.91 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7552414 | 0.87 | RARG (0.75) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7552408 | 0.87 | RARG (0.75) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL9868148 | 0.86 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL9860673 | 0.86 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7545484 | 0.86 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL9860027 | 0.86 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL11155535 | 0.86 | RARG (0.73) | RARGRARBRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | claimed |
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | disclosed |