Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548176 | 0.88 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7545037 | 0.83 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7544468 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7544458 | 0.80 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| 2-(Phenoxymethyl)Benzothiazole SCHEMBL2245843 | 0.77 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7548813 | 0.77 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL9428008 | 0.77 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| Propionic Acid SCHEMBL9428064 | 0.77 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL8387021 | 0.77 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL11131775 | 0.77 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |