Sugi Predict

Sugi Predict / Compounds / Benzamide

Benzamide

Benzamide

SCHEMBL7544839

CC(=O)c1cccc(NC(=O)Nc2cccc(C(=O)NC3CC3)c2CN2CCC(Cc3ccc(F)cc3)CC2)c1.NC(=O)c1ccccc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCR3 P51677 20/20 0.81
▸ HTR2A P28223 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6700102 0.95 CCR3 (0.85) CCR3HTR2A
SCHEMBL6704213 0.90 CCR3 (0.86) CCR3HTR2A
SCHEMBL6701614 0.90 CCR3 (1.00) CCR3HTR2A
SCHEMBL1223806 0.87 CCR3 (1.00) CCR3HTR2A
Hydrochloric Acid SCHEMBL6704812 0.86 CCR3 (0.98) CCR3HTR2A
SCHEMBL6702213 0.84 CCR3 (1.00) CCR3HTR2A
SCHEMBL6701736 0.84 CCR3 (0.79) CCR3HTR2A
SCHEMBL6703888 0.83 CCR3 (0.82) CCR3HTR2A
Hydrochloric Acid SCHEMBL6703779 0.83 CCR3 (0.98) CCR3HTR2A
SCHEMBL6704948 0.83 CCR3 (0.78) CCR3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140087-A4 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARM CO (US) 2002-04-03 — — EP claimed
EP-1140087-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-10-10 — — EP claimed
WO-2000035454-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 — — WO claimed