Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729288 | 0.93 | NPY1R (0.73) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5730324 | 0.93 | NPY1R (0.71) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| Bromide SCHEMBL7042704 | 0.85 | NPY1R (0.80) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7039372 | 0.85 | NPY1R (0.80) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7044646 | 0.84 | NPY1R (1.00) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7045687 | 0.84 | NPY1R (1.00) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7037686 | 0.83 | NPY1R (0.98) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7043079 | 0.83 | NPY1R (0.77) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7043574 | 0.83 | NPY1R (0.80) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7041652 | 0.82 | NPY1R (0.79) | NPY1RUSP2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218379-A2 | CERTAIN ALKYLENE DIAMINE-SUBSTITUTED PYRAZOLO 1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO 1,5-a]-1,3,5-TRIAZINES | NEUROGEN CORPORATION (US) | 2002-07-03 | — | — | EP | claimed |
| US-6372743-B1 | EATING DISORDERS, HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | NEUROGEN CORPORATION | 2002-04-16 | — | — | US | claimed |
| WO-2001023387-A2 | CERTAIN ALKYLENE DIAMINE-SUBSTITUTED PYRAZOLO[1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO[1,5-a]-1,3,5-TRIAZINES | NEUROGEN CORPORATION (US) | 2001-04-05 | — | — | WO | claimed |