SCHEMBL7545129

SCHEMBL7545129

CCCOc1ccc(C(=NOC)C(C)=NOCc2ccccc2C(=NOC)C(=O)NC)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.43
PARP10 Q53GL7 2/20 0.39
PARP14 Q460N5 1/20 0.39
KAT6A Q92794 2/20 0.38
MAOB P27338 3/20 0.35
PARP15 Q460N3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7504772 0.94 HIF1A (0.44) HIF1APARP10PARP14KAT6AMAOB
SCHEMBL7493427 0.91 HIF1A (0.43) HIF1AKAT6A
SCHEMBL7501613 0.91 HIF1A (0.54) HIF1APARP10PARP14KAT6AMAOB
SCHEMBL7498636 0.91 HIF1A (0.42) HIF1APARP10PARP14PARP15
SCHEMBL7505105 0.87 HIF1A (0.43) HIF1A
SCHEMBL7500240 0.86 HIF1A (0.40) HIF1APARP10PARP14
SCHEMBL7741766 0.85 HIF1A (0.43) HIF1APARP10PARP14KAT6A
SCHEMBL7741767 0.85 HIF1A (0.43) HIF1APARP10PARP14KAT6A
SCHEMBL7502688 0.85 HIF1A (0.55) HIF1APARP10PARP14KAT6AMAOB
SCHEMBL7501818 0.84 HIF1A (0.45) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed