Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549709 | 0.88 | PDE10A (0.43) | PDE10ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7548379 | 0.87 | PDE10A (0.43) | PDE10ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7547396 | 0.87 | PDE10A (0.43) | PDE10AALDH1A1KDM4ENPC1TSHR | |
| SCHEMBL7543091 | 0.85 | PDE10A (0.42) | PDE10ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7547319 | 0.84 | PDE10A (0.41) | PDE10ASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7546594 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7545911 | 0.83 | PDE10A (0.45) | PDE10ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7548347 | 0.83 | PDE10A (0.45) | PDE10ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7548833 | 0.80 | PDE10A (0.47) | PDE10ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7541024 | 0.80 | PDE10A (0.43) | PDE10AALDH1A1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |