SCHEMBL7545888 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	3/20	0.42

▸	KMT2A	Q03164	3/20	0.42

▸	MAPT	P10636	3/20	0.41

▸	ITGB1	P05556	6/20	0.41

▸	ITGA4	P13612	6/20	0.41

▸	PDF	Q9HBH1	1/20	0.41

▸	ALDH1A1	P00352	1/20	0.40

▸	HTT	P42858	1/20	0.40

▸	SSTR3	P32745	1/20	0.40

▸	ACE	P12821	1/20	0.40

▸	CTSL	P07711	2/20	0.40

▸	NPSR1	Q6W5P4	1/20	0.39

▸	MYOC	Q99972	1/20	0.39

▸	RORC	P51449	1/20	0.39

▸	ANPEP	P15144	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7544791	0.91	MEN1 (0.39)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7548231	0.91	MEN1 (0.39)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7542159	0.91	MEN1 (0.39)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7544796	0.91	MEN1 (0.39)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7545857	0.91	ITGB1 (0.42)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7545860	0.91	ITGB1 (0.42)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7543347	0.91	ACE (0.45)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7542054	0.91	MEN1 (0.41)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7547950	0.91	ACE (0.46)	MEN1KMT2AMAPTITGB1ITGA4
SCHEMBL7539323	0.91	MEN1 (0.39)	MEN1KMT2AMAPTITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1209147-A1	CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT	TORAY INDUSTRIES, INC. (JP)	2002-05-29	—	—	EP	disclosed