SCHEMBL75461

SCHEMBL75461

COC(=O)C1CC2C=CC1C2

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.58
LMNA P02545 1/20 0.58
ALDH1A1 P00352 6/20 0.49
HPGD P15428 1/20 0.49
KMT2A Q03164 2/20 0.48
POLB P06746 2/20 0.48
RAB9A P51151 1/20 0.45
APEX1 P27695 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
ESR2 Q92731 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
THRB P10828 1/20 0.41
MAPK1 P28482 1/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19220253 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL18628996 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL19860432 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL11509527 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL24908346 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL13714939 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL23016645 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL29483886 1.00 KDM4E (0.58) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL4321358 0.93 KDM4E (0.51) KDM4ELMNAALDH1A1HPGDKMT2A
Methylene Chloride SCHEMBL27618260 0.93 KDM4E (0.51) KDM4ELMNAALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3192 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058587-A Preparation method of 2,3' -bisindole compound 湖北科技学院 2025-05-30 CN claimed
EP-2970522-B1 IN-MOLD COATING OF ROMP POLYMERS MATERIA INC (US) 2025-05-21 EP claimed
CN-120005271-A Cycloolefin copolymer/carbon nano tube hybrid material modified oil-water separation sponge 重庆理工大学 2025-05-16 CN claimed
CN-120001231-A Cycloolefin block copolymer oil-water separation film 重庆理工大学 2025-05-16 CN claimed
CN-119751823-A Method for preparing functionalized polyolefin in high flux based on macro-micro reactor 南京工业大学 2025-04-04 CN claimed
US-20250034290-A1 Functional Cyclic Olefin Polymer, Process for Obtaining the Same and Compositions Containing the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-30 US claimed
CN-119264029-A Preparation method of indole C2-position methylation 湖北科技学院 2025-01-07 CN claimed
CN-119241533-A Preparation method of tetrahydro-gamma-carboline 湖北科技学院 2025-01-03 CN claimed
CN-119101214-A Cycloolefin metathesis composition and polymerization method thereof 道生天合材料科技(上海)股份有限公司 2024-12-10 CN claimed
CN-119100969-A Preparation method of C2-site alkylated indole compound 湖北科技学院 2024-12-10 CN claimed
CN-1186080-A Process for production of hydrogenated ring-opened metathesis polymers BAYER AG (DE) 1998-07-01 CN claimed
EP-0828764-A1 ADDITION POLYMERS OF POLYCYCLOOLEFINS CONTAINING FUNCTIONAL SUBSTITUENTS The B.F. Goodrich Company (US) 1998-03-18 EP claimed
WO-1996037526-A1 ADDITION POLYMERS OF POLYCYCLOOLEFINS CONTAINING FUNCTIONAL SUBSTITUENTS THE B.F. GOODRICH COMPANY (US) 1996-11-28 WO claimed
EP-0488135-A2 Bulk polymerizable reaction solutions NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP claimed
EP-0263425-A1 A process and composition for metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1988-04-13 EP claimed
US-4329270-A POLYNORBORNENE DIRIVATIVES EASTMAN KODAK COMPANY (US) 1982-05-11 US claimed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US claimed
US-4176220-A COORDINATION CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US claimed
US-4106943-A RING-OPENED POLYMER OR COPOLYMER OF NORBORNENE DERIVATIVE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1978-08-15 US claimed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US claimed