SCHEMBL7546288

SCHEMBL7546288

NC(=O)[C@@H]1CC=CC[C@@H]1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 2/20 0.46
POLB P06746 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 3/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
TSHR P16473 2/20 0.42
HSD17B10 Q99714 1/20 0.42
GABRR1 P24046 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546291 1.00 GRM4 (0.46) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL7546289 1.00 GRM4 (0.46) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL2593887 0.89 GRM4 (0.52) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL2674256 0.89 GRM4 (0.52) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL31737192 0.87 POLB (0.54) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL60588 0.87 POLB (0.54) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL10739512 0.87 POLB (0.54) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL174303 0.87 POLB (0.54) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL10739509 0.87 POLB (0.54) GRM4POLBTDP1ALDH1A1KDM4E
SCHEMBL14433706 0.87 POLB (0.54) GRM4POLBTDP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889988-B1 ALDEHYDE-MODIFIED CELLULOSIC FIBERS FOR PAPER PRODUCTS HAVING HIGH INITIAL WET STRENGTH PROCTER & GAMBLE (US) 2002-06-12 EP claimed
EP-0889988-A2 ALDEHYDE-MODIFIED CELLULOSIC FIBERS FOR PAPER PRODUCTS HAVING HIGH INITIAL WET STRENGTH THE PROCTER & GAMBLE COMPANY (US) 1999-01-13 EP claimed
US-5698688-A ESTERIFICATION; OXIDATION; WET STRENGTH THE PROCTER & GAMBLE COMPANY (US) 1997-12-16 US claimed
WO-1997036037-A2 ALDEHYDE-MODIFIED CELLULOSIC FIBERS FOR PAPER PRODUCTS HAVING HIGH INITIAL WET STRENGTH THE PROCTER & GAMBLE COMPANY (US) 1997-10-02 WO claimed
US-5656746-A Temporary wet strength polymers from oxidized reaction product of polyhydroxy polymer and 1,2-disubstituted carboxylic alkene THE PROCTOR & GAMBLE COMPANY (US) 1997-08-12 US claimed
EP-0216347-B1 A MODIFIED BLOCK COPOLYMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-11-07 EP claimed
CN-115353481-A Catalytic synthesis method of cis-1, 2,3, 6-tetrahydrophthalimide 宁夏格瑞精细化工有限公司 2022-11-18 CN disclosed
EP-0085115-A1 MODIFIED BLOCK COPOLYMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-08-10 EP disclosed