Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.61 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.60 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 2/20 | 0.55 |
| ▸ | MC5R | P33032 | 2/20 | 0.55 |
| ▸ | MC3R | P41968 | 2/20 | 0.55 |
| ▸ | MC1R | Q01726 | 2/20 | 0.55 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSH | P09668 | 1/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.52 |
| ▸ | GRPR | P30550 | 1/20 | 0.52 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321079 | 1.00 | GNRHR (0.61) | GNRHRC5AR1ABCC2PTGS1MC4R | |
| SCHEMBL29942618 | 0.95 | C5AR1 (0.64) | GNRHRC5AR1ABCC2PTGS1MC4R | |
| SCHEMBL30271248 | 0.95 | C5AR1 (0.64) | GNRHRC5AR1ABCC2PTGS1MC4R | |
| SCHEMBL29459900 | 0.93 | C5AR1 (0.65) | GNRHRC5AR1ABCC2PTGS1MC4R | |
| SCHEMBL5200355 | 0.93 | GNRHR (0.64) | GNRHRC5AR1ABCC2PTGS1KISS1R | |
| SCHEMBL11033870 | 0.92 | C5AR1 (0.65) | GNRHRC5AR1ABCC2PTGS1MC4R | |
| Deslorelin SCHEMBL25353366 | 0.92 | GNRHR (0.74) | GNRHRC5AR1ABCC2PTGS1APLNR | |
| Leuprolide SCHEMBL14190828 | 0.92 | GNRHR (0.74) | GNRHRC5AR1ABCC2PTGS1APLNR | |
| Leuprolide SCHEMBL172917 | 0.92 | GNRHR (0.74) | GNRHRC5AR1ABCC2PTGS1APLNR | |
| Deslorelin SCHEMBL59413 | 0.92 | GNRHR (0.74) | GNRHRC5AR1ABCC2PTGS1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039996-A2 | COMBINED THERAPY AGAINST TUMORS COMPRISING ESTRAMUSTINE PHOSPHATE AND LHRH AGONISTS OR ANTAGONISTS | PHARMACIA & UP JOHN COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |