Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.77 |
| ▸ | HTR2B | P41595 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15126141 | 1.00 | HTR2C (0.77) | HTR2CHTR2BKDM4ENPC1RAB9A | |
| SCHEMBL7548757 | 0.96 | HTR2C (0.71) | HTR2CHTR2BKDM4ENPC1RAB9A | |
| SCHEMBL30604550 | 0.89 | HTR2C (0.81) | HTR2CHTR2BKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30001608 | 0.88 | HTR2C (0.80) | HTR2CHTR2BKDM4ENPC1RAB9A | |
| SCHEMBL21540823 | 0.87 | HTR2C (0.60) | HTR2CHTR2BKDM4ENPC1RAB9A | |
| SCHEMBL24653087 | 0.86 | HTR2C (0.70) | HTR2CHTR2BKDM4ERAB9AHDAC1 | |
| SCHEMBL17268026 | 0.86 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1GID4 | |
| SCHEMBL21206860 | 0.86 | HTR2C (0.70) | HTR2CHTR2BKDM4ERAB9AHDAC1 | |
| SCHEMBL30524847 | 0.86 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1GID4 | |
| SCHEMBL24648976 | 0.86 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1GID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |