SCHEMBL7546943

SCHEMBL7546943

C/C=C\c1ccc(Oc2ccccc2)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 2/20 0.55
TTR P02766 3/20 0.53
BACE1 P56817 1/20 0.51
TYR P14679 1/20 0.50
CNR2 P34972 1/20 0.47
ALOX5 P09917 1/20 0.46
NQO1 P15559 1/20 0.46
NQO2 P16083 1/20 0.46
APP P05067 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546946 1.00 TUBB1 (0.55) TUBB1TTRBACE1TYRCNR2
SCHEMBL17627677 0.81 TTR (0.69) TUBB1TTRTYRNQO2
Diphenylether SCHEMBL7719408 0.80 TYR (0.77) TTRTYRALOX5APP
SCHEMBL7263488 0.80 TTR (0.64) TUBB1TTRBACE1
SCHEMBL25205842 0.78 BCHE (0.57) TUBB1TTRBACE1
SCHEMBL30382819 0.78 BCHE (0.57) TUBB1TTRBACE1
SCHEMBL1682625 0.78 TYR (0.73) TUBB1TYRALOX5NQO1NQO2
SCHEMBL3371209 0.78 TYR (0.73) TUBB1TYRALOX5NQO1NQO2
SCHEMBL1682661 0.78 TYR (0.73) TUBB1TYRALOX5NQO1NQO2
SCHEMBL29639723 0.78 TYR (0.73) TUBB1TYRALOX5NQO1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002050008-A2 NON-HALOGENATED PHENOXY AND/OR BENZYLOXY PHENOLS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO claimed
WO-2002050008-A2 NON-HALOGENATED PHENOXY AND/OR BENZYLOXY PHENOLS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO disclosed