SCHEMBL7547013

SCHEMBL7547013

O=C(CBr)NCCOCCOCCNC(=O)CBr

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.42
CA2 P00918 6/20 0.38
CA12 O43570 4/20 0.38
CA1 P00915 4/20 0.38
CA4 P22748 4/20 0.38
CA9 Q16790 4/20 0.38
CA14 Q9ULX7 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
LMNA P02545 2/20 0.35
HDAC3 O15379 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC7 Q8WUI4 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC10 Q969S8 2/20 0.35
HDAC11 Q96DB2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14005135 0.92 MEN1 (0.41) MEN1KMT2ASMN1; SMN2CA2CA12
SCHEMBL26255469 0.92 MEN1 (0.44) MEN1KMT2ASMN1; SMN2CA2CA12
SCHEMBL15757921 0.92 SMN1; SMN2 (0.42) MEN1KMT2ASMN1; SMN2CA2CA12
SCHEMBL27138688 0.92 SMN1; SMN2 (0.42) MEN1KMT2ASMN1; SMN2CA2CA12
SCHEMBL16853233 0.91 MEN1 (0.39) MEN1KMT2ASMN1; SMN2CA2CA12
SCHEMBL24796096 0.90 MEN1 (0.40) MEN1KMT2ASMN1; SMN2CA2CA12
SCHEMBL20197917 0.90 KDM4E (0.46) MEN1KMT2ASMN1; SMN2CA2L3MBTL1
SCHEMBL21748011 0.90 KDM4E (0.46) MEN1KMT2ASMN1; SMN2CA2L3MBTL1
SCHEMBL18120313 0.90 MEN1 (0.44) MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E
SCHEMBL24894030 0.90 MEN1 (0.44) MEN1KMT2ASMN1; SMN2CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules Belyntic GmbH (DE) 2025-11-18 US claimed
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules Belyntic GmbH (DE) 2025-11-18 US disclosed
EP-4010352-B1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES GYROS PROTEIN TECH AB (SE) 2023-10-18 EP disclosed
US-11730726-B2 Dimeric immuno-modulatory compounds against cereblon-based mechanisms H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2023-08-22 US disclosed
US-20220363713-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES Belyntic GmbH (DE) 2022-11-17 US disclosed
EP-0815091-B1 POLYAZACYCLOALKANE COMPOUNDS NYCOMED IMAGING AS (NO) 2002-06-12 EP disclosed
US-5705637-A Polyazacycloalkane compounds NYCOMED IMAGING AS (NO) 1998-01-06 US disclosed
US-5677446-A Polyazacycloalkane compounds NYCOMED IMAGING AS (NO) 1997-10-14 US disclosed
US-5631368-A Polyazacycloalkane compounds NYCOMED IMAGING AS (NO) 1997-05-20 US disclosed
WO-1996028433-A1 POLYAZACYCLOALKANE COMPOUNDS NYCOMED IMAGING A.S (NO) 1996-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730726-B2 Dimeric immuno-modulatory compounds against cereblon-based mechanisms CRBN, CD4, CD74 MEN1 2966/4885KMT2A 3583/4885SMN1; SMN2 1672/4885
US-20220363713-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES PTMS, VIP, HM13 MEN1 2426/4885KMT2A 2598/4885SMN1; SMN2 3665/4885
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules PTMS, VIP, HM13 MEN1 2614/4885KMT2A 2599/4885SMN1; SMN2 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.