SCHEMBL7547104

SCHEMBL7547104

CCCCCCCN1CC[C@@H](NC[C@H](O)c2ccnc3ccc(OC)cc23)[C@@H](C(N)=O)C1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.52
CCR8 P51685 1/20 0.48
KCNH2 Q12809 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7498961 0.89 KCNH2 (0.49) SLC2A1KCNH2
SCHEMBL5852408 0.88 SLC2A1 (0.50) SLC2A1CCR8KCNH2
SCHEMBL7548762 0.88 SLC2A1 (0.50) SLC2A1CCR8KCNH2
SCHEMBL5853742 0.85 SLC2A1 (0.58) SLC2A1CCR8KCNH2
SCHEMBL5852476 0.85 SLC2A1 (0.58) SLC2A1CCR8KCNH2
SCHEMBL7549582 0.79 SLC2A1 (0.58) SLC2A1KCNH2
SCHEMBL6964635 0.79 SLC2A1 (0.55) SLC2A1CCR8KCNH2
SCHEMBL6964639 0.79 SLC2A1 (0.55) SLC2A1CCR8KCNH2
SCHEMBL6964644 0.79 SLC2A1 (0.55) SLC2A1CCR8KCNH2
SCHEMBL7508875 0.78 SLC2A1 (0.45) SLC2A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202987-A2 QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS SMITHKLINE BEECHAM PLC (GB) 2002-05-08 EP disclosed
WO-2001007433-A2 QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS SMITHKLINE BEECHAM P.L.C. (GB) 2001-02-01 WO disclosed