Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 4/20 | 0.31 |
| ▸ | PPARA | Q07869 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553915 | 0.90 | CYP1A2 (0.32) | CYP1A2MAPTCYP2C9KMT2ABAZ2B | |
| SCHEMBL9350650 | 0.90 | GAA (0.33) | CYP1A2MAPTCYP2C9KMT2ABAZ2B | |
| SCHEMBL9351415 | 0.88 | BAZ2B (0.33) | CYP1A2MAPTCYP2C9KMT2ABAZ2B | |
| SCHEMBL6553643 | 0.88 | BAZ2B (0.38) | CYP1A2MAPTCYP2C9KMT2ABAZ2B | |
| SCHEMBL2965779 | 0.88 | PPARD (0.33) | POLBAPEX1PPARDPPARAPPARG | |
| SCHEMBL31581569 | 0.88 | PPARD (0.32) | POLBAPEX1PPARDPPARAPPARG | |
| SCHEMBL25361650 | 0.87 | PPARD (0.31) | PPARDPPARAPPARG | |
| SCHEMBL25243907 | 0.85 | POLB (0.32) | MAPTPOLBAPEX1PPARDPPARA | |
| SCHEMBL22745804 | 0.85 | MAPT (0.36) | CYP1A2MAPTCYP2C9KMT2ABAZ2B | |
| SCHEMBL9350427 | 0.83 | NOTUM (0.40) | CYP1A2MAPTCYP2C9KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436680-B1 | HETEROCYCLIC COMPOUNDS | CIBA GEIGY AG (CH) | 1994-09-07 | — | — | EP | claimed |
| EP-1206185-A1 | COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS | Aventis CropScience GmbH (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001008487-A1 | COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-08 | — | — | WO | disclosed |