Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.30 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64811 | 0.94 | ATM (0.46) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL9576346 | 0.93 | ATM (0.38) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL9576334 | 0.90 | ATM (0.36) | ATMHCAR2APP | |
| SCHEMBL9576547 | 0.90 | ATM (0.36) | ATMHCAR2APP | |
| SCHEMBL1632990 | 0.89 | ATM (0.44) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL8640131 | 0.89 | ATM (0.44) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL15421827 | 0.89 | ATM (0.44) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL10839217 | 0.87 | ATM (0.43) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL11075201 | 0.85 | ATM (0.39) | ATMHCAR2APPMAPTRAB9A | |
| SCHEMBL9763742 | 0.84 | ATM (0.41) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |