⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377855 | 1.00 | — | — | |
| SCHEMBL1132484 | 0.81 | — | — | |
| SCHEMBL8439092 | 0.81 | — | — | |
| SCHEMBL15364102 | 0.78 | — | — | |
| SCHEMBL14928787 | 0.78 | — | — | |
| SCHEMBL13452784 | 0.78 | — | — | |
| SCHEMBL17921632 | 0.78 | — | — | |
| SCHEMBL13452778 | 0.78 | — | — | |
| SCHEMBL4159271 | 0.78 | — | — | |
| SCHEMBL13452759 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165156-A | Concentrated induced polymerization proton acid type polyion liquid and preparation method and application thereof | 湖南大学 | 2024-06-11 | — | — | CN | claimed |
| US-20200216417-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2020-07-09 | — | — | US | disclosed |
| US-20190185451-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC | 2019-06-20 | — | — | US | disclosed |
| CN-109069984-A | Morpholinyl hindered amine compound is in the purposes being selectively removed in hydrogen sulfide | 巴斯夫欧洲公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-1218379-A2 | CERTAIN ALKYLENE DIAMINE-SUBSTITUTED PYRAZOLO 1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO 1,5-a]-1,3,5-TRIAZINES | NEUROGEN CORPORATION (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023387-A2 | CERTAIN ALKYLENE DIAMINE-SUBSTITUTED PYRAZOLO[1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO[1,5-a]-1,3,5-TRIAZINES | NEUROGEN CORPORATION (US) | 2001-04-05 | — | — | WO | disclosed |