Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069 | 0.94 | CHRM2 (0.39) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL7185203 | 0.92 | CHRM2 (0.43) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL18912893 | 0.92 | LCK (0.46) | LCKCHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL23127777 | 0.89 | LCK (0.39) | LCKCHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL19754837 | 0.89 | LCK (0.39) | LCKCHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL15557660 | 0.89 | CHRM2 (0.48) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL34566 | 0.88 | — | — | |
| SCHEMBL8372465 | 0.88 | CHRM2 (0.39) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL1273416 | 0.88 | — | — | |
| SCHEMBL2595780 | 0.86 | CHRM2 (0.52) | CHRM2DNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567195-B1 | DENDRIMER CONJUGATES FOR SELECTIVE SOLUBILISATION OF PROTEIN AGGREGATES | UPFRONT CHROMATOGRAPHY AS (DK) | 2010-10-27 | — | — | EP | disclosed |
| EP-0885131-B1 | NEAR INFRARED FLUORESCENT SECURITY THERMAL TRANSFER PRINTING AND MARKING RIBBONS | ISOTAG TECHNOLOGY INC (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6174400-B1 | PHTHALOCYANINE DYES | ISOTAG TECHNOLOGY, INC. | 2001-01-16 | — | — | US | disclosed |
| EP-0885131-A1 | NEAR INFRARED FLUORESCENT SECURITY THERMAL TRANSFER PRINTING AND MARKING RIBBONS | EASTMAN CHEMICAL COMPANY (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032733-A1 | NEAR INFRARED FLUORESCENT SECURITY THERMAL TRANSFER PRINTING AND MARKING RIBBONS | EASTMAN CHEMICAL COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |