SCHEMBL754761

SCHEMBL754761

CO[Si](CCCOCCC1CO1)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28426665 0.93 TSHR (0.39) MEN1KMT2ATSHRSMN1; SMN2ALDH1A1
SCHEMBL13497982 0.89 MEN1 (0.40) MEN1KMT2ATSHRSMN1; SMN2ALDH1A1
SCHEMBL15239864 0.88 EPHX1 (0.39) MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL31520329 0.86 TSHR (0.39) MEN1KMT2ATSHRSMN1; SMN2ALDH1A1
SCHEMBL25276079 0.84 TSHR (0.57) MEN1KMT2ATSHRSMN1; SMN2ALDH1A1
SCHEMBL1721308 0.84 TSHR (0.57) MEN1KMT2ATSHRSMN1; SMN2ALDH1A1
SCHEMBL27214517 0.84 TSHR (0.57) MEN1KMT2ATSHRSMN1; SMN2ALDH1A1
SCHEMBL27615 0.84 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL284717 0.84 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL5958589 0.84 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9125968-B2 Polymeric/ceramic composite materials for use in medical devices BOSTON SCIENTIFIC SCIMED, INC. (US) 2015-09-08 US disclosed
US-8137777-B2 Moisture curable balloon materials BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-03-20 US disclosed
US-8053515-B2 curable addition polymer having norbornene-type backbones, having oxidation resistance, used in microelectronic and optoelectronic applications PROMERUS LLC (US) 2011-11-08 US disclosed
EP-2102257-A1 DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF Promerus, LLC (US) 2009-09-23 EP disclosed
US-20080194740-A1 DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2008-08-14 US disclosed
WO-2008070774-A1 DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF PROMERUS LLC (US) 2008-06-12 WO disclosed
US-20070244501-A1 Medical balloons BOSTON SCIENTIFIC SCIMED, INC. 2007-10-18 US disclosed
US-20070224369-A1 Liquid crystal device, method for manufacturing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2007-09-27 US disclosed