SCHEMBL754780

SCHEMBL754780

Cc1cccc(S(=O)(=O)C(Br)(Br)Br)c1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.45
ACHE P22303 1/20 0.44
FBP1 P09467 8/20 0.43
ALDH1A1 P00352 4/20 0.42
EDNRA P25101 2/20 0.42
EDNRB P24530 1/20 0.42
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
MMP2 P08253 1/20 0.41
MAPK1 P28482 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92035 1.00 KMT2A (0.52) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL13941253 0.84 CA1 (0.50) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL13941252 0.83 KMT2A (0.45) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL855637 0.83 KMT2A (0.52) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL168093 0.82 KMT2A (0.50) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL11685284 0.82 KMT2A (0.50) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL5079816 0.78 KMT2A (0.55) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL29468572 0.78 KMT2A (0.59) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL822302 0.78 KMT2A (0.59) KMT2AMEN1ACHEFBP1ALDH1A1
SCHEMBL11851111 0.77 KMT2A (0.46) KMT2AMEN1ACHEFBP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
EP-2213166-A1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GmbH (DE) 2010-08-04 EP claimed
EP-2216372-B1 Compounds for preventing Ghost odour THOR GMBH (DE) 2014-06-04 EP disclosed
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP disclosed
EP-2216372-A1 Compounds for preventing Ghost odour THOR GmbH (DE) 2010-08-11 EP disclosed
EP-2213166-A1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GmbH (DE) 2010-08-04 EP disclosed