Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 18/20 | 0.77 |
| ▸ | CPT1B | Q92523 | 12/20 | 0.54 |
| ▸ | CPT2 | P23786 | 9/20 | 0.54 |
| ▸ | ALPL | P05186 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752489 | 0.87 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL751620 | 0.86 | CPT1A (0.76) | CPT1ACPT1BCPT2 | |
| SCHEMBL753189 | 0.81 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| Potassium SCHEMBL751515 | 0.81 | CPT1A (0.80) | CPT1ACPT1BCPT2 | |
| SCHEMBL751513 | 0.81 | CPT1A (0.80) | CPT1ACPT1BCPT2ALPL | |
| SCHEMBL13571495 | 0.80 | CPT1A (0.66) | CPT1ACPT1BCPT2 | |
| SCHEMBL765754 | 0.78 | CPT1A (0.66) | CPT1ACPT1BCPT2ALPL | |
| Potassium Ion SCHEMBL751514 | 0.78 | CPT1A (0.73) | CPT1ACPT1BCPT2ALPL | |
| SCHEMBL753237 | 0.77 | CPT1A (0.83) | CPT1ACPT1BCPT2 | |
| SCHEMBL751022 | 0.76 | CPT1A (1.00) | CPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10611775-B2 | Thiophene derivatives | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2020-04-07 | — | — | US | disclosed |
| US-20190322684-A1 | THIOPHENE DERIVATIVES | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2019-10-24 | — | — | US | disclosed |
| US-20170197982-A1 | THIOPHENE DERIVATIVES | GANZHOU HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2017-07-13 | — | — | US | disclosed |
| US-9630975-B2 | Thiophene derivatives | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2017-04-25 | — | — | US | disclosed |
| US-8952178-B2 | Thiophene derivatives | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2015-02-10 | — | — | US | disclosed |
| US-20140255342-A1 | THIOPHENE DERIVATIVES | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2014-09-11 | — | — | US | disclosed |
| EP-2431371-B1 | THIOPHENE DERIVATIVES | TIANJIN HEMAY BIO TECH CO LTD (CN) | 2013-10-09 | — | — | EP | disclosed |
| US-20120107269-A1 | THIOPHENE DERIVATIVES | Tianjin Hemay Biotech Co., Ltd (CN) | 2012-05-03 | — | — | US | disclosed |
| EP-2431371-A1 | THIOPHENE DERIVATIVES | Tianjin Hemay Bio-Tech Co., Ltd. (CN) | 2012-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107269-A1 | THIOPHENE DERIVATIVES | TSHR, RB1, TAS2R7 | CPT1A 2619/4885CPT1B 3243/4885CPT2 2905/4885 |
| US-10611775-B2 | Thiophene derivatives | TSHR, RB1, TAS2R7 | CPT1A 2619/4885CPT1B 3243/4885CPT2 2905/4885 |
| US-20170197982-A1 | THIOPHENE DERIVATIVES | TSHR, RB1, TAS2R7 | CPT1A 2619/4885CPT1B 3243/4885CPT2 2905/4885 |
| US-20140255342-A1 | THIOPHENE DERIVATIVES | TSHR, RB1, TAS2R7 | CPT1A 2619/4885CPT1B 3243/4885CPT2 2905/4885 |
| US-20190322684-A1 | THIOPHENE DERIVATIVES | TSHR, RB1, TAS2R7 | CPT1A 2619/4885CPT1B 3243/4885CPT2 2905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.