Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA4 | P22748 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527051 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL7548526 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8259026 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL7551125 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL7541404 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL7549199 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8260233 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL7532450 | 0.98 | CA12 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL457477 | 0.98 | — | — | |
| Nitric Acid SCHEMBL2564368 | 0.91 | CA12 (0.42) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885886-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN SEIFUN GROUP INC (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5972943-A | N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885886-A1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |