SCHEMBL7548693

SCHEMBL7548693

CCCCOC(=O)N(C(=O)OC)c1ccc(OCc2nc3ccccc3o2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
HSD17B10 Q99714 2/20 0.43
LMNA P02545 2/20 0.43
F2 P00734 1/20 0.43
MIF P14174 1/20 0.43
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PDE10A Q9Y233 1/20 0.42
TP53 P04637 4/20 0.40
HSP90AA1 P07900 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
P2RY14 Q15391 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PPARD Q03181 3/20 0.38
PPARG P37231 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7543738 0.96 TP53 (0.43) MAPTALDH1A1KMT2AHSD17B10LMNA
SCHEMBL7541458 0.93 PDE10A (0.44) ALDH1A1KMT2AHSD17B10LMNATDP1
SCHEMBL7548833 0.92 PDE10A (0.47) MAPTALDH1A1HSD17B10LMNATDP1
SCHEMBL7550323 0.88 PDE10A (0.42) ALDH1A1HSD17B10LMNATDP1PDE10A
SCHEMBL7549521 0.88 PDE10A (0.43) MAPTALDH1A1HSD17B10LMNATDP1
SCHEMBL7542088 0.87 PDE10A (0.44) ALDH1A1HSD17B10LMNATDP1PDE10A
SCHEMBL7548710 0.85 PDE10A (0.44) MAPTALDH1A1KMT2AHSD17B10LMNA
SCHEMBL7545435 0.85 PDE10A (0.47) MAPTLMNATDP1PDE10ATP53
SCHEMBL7545911 0.83 PDE10A (0.45) MAPTALDH1A1HSD17B10LMNATDP1
SCHEMBL7542014 0.83 PDE10A (0.51) MAPTALDH1A1HSD17B10LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed