Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.62 |
| ▸ | RORC | P51449 | 12/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754666 | 0.88 | NR3C2 (0.68) | NR3C2AR | |
| SCHEMBL4516280 | 0.88 | NR3C2 (0.68) | NR3C2AR | |
| SCHEMBL755857 | 0.81 | NR3C2 (0.80) | NR3C2AR | |
| SCHEMBL756315 | 0.81 | NR3C2 (0.75) | NR3C2AR | |
| SCHEMBL755904 | 0.80 | NR3C2 (0.77) | NR3C2AR | |
| SCHEMBL755047 | 0.79 | NR3C2 (0.72) | NR3C2AR | |
| SCHEMBL743757 | 0.79 | NR3C2 (0.75) | NR3C2AR | |
| SCHEMBL753564 | 0.79 | NR3C2 (0.75) | NR3C2AR | |
| SCHEMBL754877 | 0.79 | NR3C2 (0.63) | NR3C2AR | |
| SCHEMBL754187 | 0.78 | NR3C2 (0.74) | NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984345-B9 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-1984345-B1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-08-31 | — | — | EP | disclosed |