Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544564 | 1.00 | KMT2A (0.44) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7687734 | 1.00 | KMT2A (0.44) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7544561 | 1.00 | KMT2A (0.44) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7544558 | 1.00 | KMT2A (0.44) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7545814 | 0.99 | KMT2A (0.43) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7548338 | 0.99 | KMT2A (0.43) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7545820 | 0.99 | KMT2A (0.43) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7548341 | 0.99 | KMT2A (0.43) | KMT2AMEN1ABCG2CTSDLMNA | |
| SCHEMBL7695200 | 0.92 | KMT2A (0.45) | KMT2AMEN1ABCG2LMNAKDM4E | |
| SCHEMBL7550660 | 0.91 | KMT2A (0.46) | KMT2AMEN1ABCG2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053546-A1 | HETEROCYCLE DERIVATIVES AS PPAR-GAMMA AGONISTS | ADVANCED SYNTECH, LLC (US) | 2002-07-11 | — | — | WO | claimed |
| US-20020082263-A1 | Heterocycle derivatives as PPAR-gamma agonists | ADVANCED SYNTECH LLC | 2002-06-27 | — | — | US | claimed |
| WO-2002053546-A1 | HETEROCYCLE DERIVATIVES AS PPAR-GAMMA AGONISTS | ADVANCED SYNTECH, LLC (US) | 2002-07-11 | — | — | WO | disclosed |
| US-20020082263-A1 | Heterocycle derivatives as PPAR-gamma agonists | ADVANCED SYNTECH LLC | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082263-A1 | Heterocycle derivatives as PPAR-gamma agonists | PPARG, PPARD, PPARA | KMT2A 2543/4885MEN1 4629/4885ABCG2 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.