Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.86 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.86 |
| ▸ | MAPT | P10636 | 1/20 | 0.86 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.86 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.84 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.84 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.84 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.84 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.84 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.84 |
| ▸ | FPR1 | P21462 | 1/20 | 0.84 |
| ▸ | FPR3 | P25089 | 1/20 | 0.84 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.84 |
| ▸ | HTR1D | P28221 | 1/20 | 0.84 |
| ▸ | HTR2A | P28223 | 1/20 | 0.84 |
| ▸ | HTR2C | P28335 | 1/20 | 0.84 |
| ▸ | TSPO | P30536 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4911001 | 0.99 | OPRL1 (0.98) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4917164 | 0.94 | OPRL1 (0.98) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4920232 | 0.94 | OPRL1 (0.98) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4918400 | 0.94 | OPRL1 (0.98) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL4920043 | 0.93 | OPRL1 (0.88) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL4916932 | 0.93 | OPRL1 (0.88) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4916990 | 0.93 | OPRL1 (0.98) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4918190 | 0.93 | OPRL1 (0.88) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4914573 | 0.93 | OPRL1 (0.98) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| Hydrochloric Acid SCHEMBL4920691 | 0.93 | OPRL1 (0.86) | OPRL1OPRM1OPRK1MAPTOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002047726-A2 | PHARMACEUTICAL COMPOSITION CONTAINING AN ACTIVE WITH A HEMOLYTIC ACTION AND A SURFACTANT | JAPAN TOBACCO INC. (JP) | 2002-06-20 | — | — | WO | disclosed |