SCHEMBL7549552

SCHEMBL7549552

NO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.60
HINT1 P49773 4/20 0.58
NT5E P21589 1/20 0.58
GSK3A P49840 2/20 0.54
RPS6KA3 P51812 2/20 0.54
MAPK14 Q16539 2/20 0.54
PNP P00491 2/20 0.54
TGM2 P21980 1/20 0.54
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
STING1 Q86WV6 2/20 0.52
PDE3B Q13370 1/20 0.52
PDE3A Q14432 1/20 0.52
PAX8 Q06710 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL545904 1.00 HPGD (0.60) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL23880677 0.92 HPGD (0.63) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL6537060 0.92 HPGD (0.60) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL14842253 0.92 HPGD (0.63) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL7614834 0.91 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL20582919 0.91 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL546454 0.91 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL21179102 0.91 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL12300426 0.91 HPGD (0.61) HPGDHINT1NT5EGSK3ARPS6KA3
SCHEMBL18512866 0.91 HPGD (0.61) HPGDHINT1NT5EGSK3ARPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002053591-A METHOD FOR PRODUCING 2'-O-ALKYLGUANOSINE YAMASA SHOYU CO LTD 2002-02-19 JP disclosed