⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198272 | 0.76 | ATM (0.33) | — | |
| SCHEMBL4063260 | 0.74 | — | — | |
| SCHEMBL4065727 | 0.74 | — | — | |
| SCHEMBL7761724 | 0.73 | PSEN1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7760855 | 0.73 | — | — | |
| SCHEMBL4232585 | 0.73 | — | — | |
| SCHEMBL4232582 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7762540 | 0.72 | — | — | |
| SCHEMBL4245801 | 0.71 | — | — | |
| SCHEMBL4245803 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259484-A1 | CARBOXAMIDES USEFUL AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND OF APOLIPOPROTEIN B SECRETION | Novartis AG (CH) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001053260-A1 | CARBOXAMIDES USEFUL AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND OF APOLIPOPROTEIN B SECRETION | NOVARTIS AG (CH) | 2001-07-26 | — | — | WO | disclosed |