Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.62 |
| ▸ | CNR1 | P21554 | 4/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601162 | 0.88 | CNR2 (0.63) | CNR2CNR1HTR7HTTKCNH2 | |
| SCHEMBL7550761 | 0.84 | CNR2 (0.67) | CNR2CNR1PARP1HTR7HTT | |
| SCHEMBL7556631 | 0.83 | CNR1 (0.64) | CNR2CNR1KCNH2HTR4KMT2A | |
| SCHEMBL7538551 | 0.82 | CNR2 (0.47) | CNR2CNR1PARP1HTR7HTT | |
| SCHEMBL30860188 | 0.80 | CNR1 (0.50) | CNR2CNR1PARP1HTR7HTT | |
| SCHEMBL10369871 | 0.80 | CNR1 (0.50) | CNR2CNR1PARP1HTR7HTT | |
| SCHEMBL13691221 | 0.79 | CNR1 (0.53) | CNR2CNR1PARP1HTR4ELANE | |
| SCHEMBL9323662 | 0.79 | CNR1 (0.53) | CNR2CNR1HTR7HTTKMT2A | |
| SCHEMBL8875998 | 0.78 | PARP1 (0.56) | CNR2CNR1PARP1ELANEALDH1A1 | |
| SCHEMBL7556638 | 0.78 | CNR2 (0.52) | CNR2CNR1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254115-A2 | CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS FOR TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES | Bristol-Myers Squibb Company (US) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058869-A2 | CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS IN TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-16 | — | — | WO | disclosed |