Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050107 | 1.00 | ATM (0.65) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7553449 | 1.00 | ATM (0.65) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7552815 | 1.00 | ATM (0.65) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7552452 | 1.00 | ATM (0.65) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7556027 | 0.98 | ATM (0.68) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL6328166 | 0.98 | ATM (0.68) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7554982 | 0.98 | ATM (0.68) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4685968 | 0.98 | ATM (0.68) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4686342 | 0.96 | ATM (0.71) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL6042389 | 0.92 | ATM (0.71) | ATML3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |