Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 12/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.44 |
| ▸ | TUBB | P07437 | 5/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551234 | 1.00 | GFER (0.45) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7617923 | 0.90 | TUBB1 (0.53) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7617918 | 0.90 | TUBB1 (0.53) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7613691 | 0.89 | TUBB1 (0.54) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7613696 | 0.89 | TUBB1 (0.54) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7552539 | 0.87 | KRAS (0.55) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7552543 | 0.87 | KRAS (0.55) | GFERALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7611033 | 0.80 | TUBB1 (0.62) | ALDH1A1LMNAMAPTMAPK1TUBB1 | |
| SCHEMBL7611037 | 0.80 | TUBB1 (0.62) | ALDH1A1LMNAMAPTMAPK1TUBB1 | |
| SCHEMBL7607438 | 0.77 | TUBB1 (0.67) | GFERALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002047604-A2 | NOVEL USE OF CHALCONE CLASS COMPOUNDS FOR INHIBITING TUMORAL MASS VASCULARIZATION | AVENTIS PHARMA S.A. (FR) | 2002-06-20 | — | — | WO | disclosed |