Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12750589 | 0.92 | PARP1 (0.74) | PARP1 | |
| SCHEMBL7554564 | 0.88 | PARP1 (0.80) | PARP1 | |
| SCHEMBL6200038 | 0.88 | PARP1 (0.80) | PARP1 | |
| SCHEMBL13475803 | 0.88 | PARP1 (0.72) | PARP1 | |
| SCHEMBL7162599 | 0.87 | PARP1 (0.73) | PARP1 | |
| SCHEMBL831830 | 0.87 | PARP1 (1.00) | PARP1 | |
| SCHEMBL7553824 | 0.86 | PARP1 (0.79) | PARP1 | |
| SCHEMBL12750631 | 0.86 | PARP1 (0.76) | PARP1 | |
| SCHEMBL7165434 | 0.85 | PARP1 (1.00) | PARP1 | |
| SCHEMBL7156700 | 0.84 | PARP1 (0.73) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222191-A2 | BENZODIAZEPIN DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001023386-A2 | BENZODIAZEPIN DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | disclosed |