SCHEMBL7552086

SCHEMBL7552086

CCCCOCCOCCOC(=O)c1ccc(O)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.81
TSHR P16473 3/20 0.81
LMNA P02545 2/20 0.81
CYP1A2 P05177 2/20 0.81
CYP2C19 P33261 2/20 0.81
SMN1; SMN2 Q16637 2/20 0.81
CYP2D6 P10635 1/20 0.81
MAPK1 P28482 1/20 0.81
NR1H2 P55055 1/20 0.81
RNASEL Q05823 1/20 0.81
ALDH1A1 P00352 2/20 0.70
CHRM1 P11229 1/20 0.70
SLC6A2 P23975 1/20 0.70
KDR P35968 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
CYP3A4 P08684 2/20 0.59
CYP2C9 P11712 1/20 0.59
PDE4D Q08499 1/20 0.59
ESR2 Q92731 2/20 0.59
CA12 O43570 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7545735 1.00 ESR1 (0.81) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL6934920 0.95 ESR1 (0.74) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL7548561 0.95 ESR1 (0.73) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL29126571 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL28965935 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL28965913 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL3343026 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL3339622 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL7546153 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL3371266 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032303-A1 Alkoxy-(0-7-(alkyloxy))alkyl p-hydroxybenzoates; high-temperature volatilization resistance and low-temperature impact resistance. NEW JAPAN CHEMICAL CO., LTD. (JP) 2002-03-14 US disclosed
US-6348563-B1 2*-ETHYLHEXYLOXYETHOXYETHYL P-HYDROXYBENZOATE COMPATIBLE WITH POLYLAUROLACTAM AND POLYUNDECANOLACTAM; LOW VOLATILITY; HEAT AND COLD RESISTANCE; IMPACT STRENGTH, FLEXIBILITY NEW JAPAN CHEMICAL CO., LTD. (JP) 2002-02-19 US disclosed
EP-0974575-A1 p-HYDROXYBENZOIC ESTERS, PLASTICIZER CONTAINING THE SAME, POLYAMIDE RESIN COMPOSITION, AND MOLDED OBJECTS NEW JAPAN CHEMICAL CO.,LTD. (JP) 2000-01-26 EP disclosed