SCHEMBL7552088

SCHEMBL7552088

COC(=O)C(Cc1nccs1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.78
CNR1 P21554 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7216832 1.00 CNR2 (0.78) CNR2CNR1
SCHEMBL7216985 0.88 CNR2 (1.00) CNR2CNR1
SCHEMBL7223450 0.85 CNR2 (1.00) CNR2CNR1
SCHEMBL7217490 0.85 CNR2 (1.00) CNR2CNR1
SCHEMBL7217492 0.85 CNR2 (1.00) CNR2CNR1
SCHEMBL7216701 0.84 CNR2 (0.88) CNR2CNR1
SCHEMBL7552082 0.83 CNR2 (0.63) CNR2CNR1
SCHEMBL7222230 0.82 CNR2 (0.91) CNR2CNR1
SCHEMBL7222265 0.82 CNR2 (0.92) CNR2CNR1
SCHEMBL7223470 0.81 CNR2 (0.75) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1254115-A2 CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS FOR TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES Bristol-Myers Squibb Company (US) 2002-11-06 EP claimed
WO-2001058869-A2 CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS IN TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES BRISTOL-MYERS SQUIBB COMPANY (US) 2001-08-16 WO claimed