Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3309093 | 0.97 | GABRR1 (0.48) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL5965334 | 0.97 | GABRR1 (0.48) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL7446931 | 0.97 | GABRR1 (0.48) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL5965326 | 0.97 | GABRR1 (0.48) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL7453042 | 0.97 | GABRR1 (0.48) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL23772898 | 0.94 | GABRR1 (0.50) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL16853135 | 0.91 | GABRR1 (0.58) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL16853370 | 0.88 | GABRR1 (0.55) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL16853123 | 0.88 | GABRR1 (0.55) | GABRR1LMNAKDM4EKMT2ACYP1A2 | |
| SCHEMBL16853138 | 0.88 | GABRR1 (0.55) | GABRR1LMNAKDM4EKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161048-A1 | Glycine substitutes and precursors for treating a psychosis | GLYTECH, INC. | 2002-10-31 | — | — | US | disclosed |
| US-6355681-B2 | ADMINISTERING TO HUMAN A SUBSTITUTE FOR GLYCINE AT THE GLYCINE-SITE OR A PRECURSOR OF SUBSTITUTE OR A GLYCINE PRECURSOR, IN AN AMOUNT SUFFICIENT TO POTENTIATE NMDA RECEPTOR-MEDIATED NEUROTRANSMISSION | GLYTECH, INC. | 2002-03-12 | — | — | US | disclosed |
| US-20020013364-A1 | GLYCINE SITE FULL AGONIST FOR TREATING A PSYCHOSIS | GLYTECH, INC. | 2002-01-31 | — | — | US | disclosed |