Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771908 | 0.95 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL4771630 | 0.93 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL5530777 | 0.92 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL7551497 | 0.91 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL5525827 | 0.91 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL5789581 | 0.90 | EDNRA (0.56) | EDNRAEDNRB | |
| SCHEMBL4766229 | 0.90 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL4773576 | 0.90 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL5536203 | 0.89 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL5532211 | 0.89 | EDNRA (0.44) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237888-A2 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001044239-A2 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB CO. (US) | 2001-06-21 | — | — | WO | claimed |