Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.67 |
| ▸ | CTSK | P43235 | 6/20 | 0.67 |
| ▸ | CTSB | P07858 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367371 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL21219305 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL29484189 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL30688549 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10050068 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL9551322 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL15671562 | 0.88 | ACE (0.72) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL2721558 | 0.88 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL1691095 | 0.88 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL21473784 | 0.88 | ACE (0.79) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001972-A1 | SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006431-A1 | SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |