Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660361 | 0.79 | EPHX2 (0.54) | WNT3ASMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL13460146 | 0.79 | MAPT (0.54) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL24670765 | 0.79 | KMT2A (0.60) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL29803595 | 0.79 | MAPT (0.54) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL24670693 | 0.79 | MAPT (0.54) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL24670882 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL24670794 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL29803695 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL29803554 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL25447362 | 0.75 | MAPT (0.60) | SMN1; SMN2MEN1KMT2ACYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171432-A1 | ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061569-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |