Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | USP7 | Q93009 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3003119 | 0.96 | ESR2 (0.71) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL26829682 | 0.91 | PDGFRB (0.72) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL24621829 | 0.91 | PDGFRB (0.72) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL29375510 | 0.91 | PDGFRB (0.72) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL708999 | 0.89 | PDGFRB (0.75) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL12580402 | 0.86 | PDGFRB (0.66) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL12580354 | 0.86 | PDGFRB (0.66) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL12580362 | 0.86 | PDGFRB (0.66) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL12580411 | 0.86 | PDGFRB (0.66) | ESR2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL12074709 | 0.85 | PDGFRB (0.70) | PDGFRBPDGFRACYP2A6BIRC5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020168403-A1 | Compositions and therapy for substance addiction | BIBERMAN RONI (IL) | 2002-11-14 | — | — | US | disclosed |
| US-20020019421-A1 | Compositions and therapy for substance addiction | BIBERMAN RONI (IL) | 2002-02-14 | — | — | US | disclosed |