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Sugi Predict / Compounds / SCHEMBL7555397

SCHEMBL7555397

SCHEMBL7555397

CC[C@H]1CCN(c2c(F)cc3c(=O)n(N)c(=O)n(C4CC4)c3c2C)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 8/20 0.46
▸ SCN5A Q14524 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1381414 0.92 KCNH2 (0.47) KCNH2SCN5A
SCHEMBL4714850 0.89 KCNH2 (0.40) KCNH2SCN5A
SCHEMBL5465780 0.89 KCNH2 (0.45) KCNH2SCN5A
SCHEMBL4502791 0.88 KCNH2 (0.47) KCNH2SCN5A
SCHEMBL6176346 0.87 KCNH2 (0.39) KCNH2SCN5A
SCHEMBL6176896 0.87 KCNH2 (0.39) KCNH2SCN5A
SCHEMBL14160482 0.87 KCNH2 (0.51) KCNH2
SCHEMBL1381298 0.87 KCNH2 (0.46) KCNH2SCN5A
SCHEMBL4518679 0.86 KCNH2 (0.42) KCNH2SCN5A
SCHEMBL6497363 0.85 KCNH2 (0.53) KCNH2SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255739-A1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 2002-11-13 — — EP disclosed
WO-2001053273-A1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 2001-07-26 — — WO disclosed